what it is
Enhance Image Analysis with User-Friendly, Powerful Software.
Accelerate Preclinical Image Analysis: Our intuitive software simplifies complex data processing, improving team productivity and ensuring consistent, reproducible results.
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Enabling research at the highest level
Imalytics powers the best research labs in the world.
Imalytics supports a wide range of preclinical applications—helping researchers extract quantitative insights from multimodal PET, SPECT, CT, MRI, and optical imaging data.
Modalities: PET, SPECT, CT, MRI, US, Optical (BLI/FLI)
Imalytics supports tumor detection, segmentation, and longitudinal tracking in a variety of cancer models. It enables visualization of tumor growth, treatment response, and metastasis using 3D visualization, VOI quantification, and multimodal fusion
Modalities: PET, SPECT, CT, MRI
Ideal for assessing tracer uptake, organ-specific distribution, and clearance. Imalytics enables %ID/ml and SUV quantification, kinetic modeling, residence time computation, and image-based dosimetry — critical for drug development and theranostics
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Modalities: PET, SPECT, CT, MRI
Ideal for assessing tracer dynamics and organ-specific pharmacokinetics in vivo. Imalytics enables dynamic (4D) image analysis, Patlak and compartmental modeling, residence time computation, and kinetic quantification of tracer behavior over time — essential for drug development, dosimetry, and translational research.
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Modalities: CT, PET, SPECT, MRI, US
Used for assessing atherosclerosis, inflammation, perfusion, and structural abnormalities. Imalytics enables vessel segmentation, volumetric analysis, and longitudinal comparison across modalities.
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Modalities: CT, MRI
Analyze bone density, morphology, and remodeling in disease models like osteoporosis or bone healing. Imalytics supports threshold-based segmentation and quantitative assessment of calcifications, trabecular thickness, porosity, and other microstructural parameters—enabling volumetric comparison and precise characterization of bone integrity across different experimental conditions.
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Modalities: MRI (functional and structural), PET, SPECT
Supports brain segmentation and regional analysis, ideal for studying neurodegenerative diseases, neuroinflammation, and brain metabolism. Imalytics handles MRI relaxometry datasets and multimodal overlays (e.g., PET-MRI fusion).
Full suite advanced software for multimodal biomedical image analysis
Built by researchers for researchers.
Imalytics Preclinical is designed from the ground up for researchers—offering fast, intuitive, and reliable image analysis. With GPU-accelerated performance, automated workflows, and interactive 3D visualization, it enables high-throughput studies and reproducible results. Imalytics helps you move from data to insight with ease and continous support.
Trusted by leading experts for advanced research solutions.
"We have found the Imalytics software to be easy to use and the support from Gremse IT is excellent. We were very impressed with the recently released voxel-based dosimetry module."
"The software is easy to learn and provides ready-to-use workflows for different applications."
"The software allows excellent analysis of multimodal imaging data sets of PET, SPECT, spectral CT and for eg. 19F-MRI combined with proton MRI."
"We have been successfully using the Imalytics software for PET/CT and CT quantification, and we are extremely satisfied with its performance. Whenever we had questions or needed clarification, the support team responded promptly and provided clear, helpful instructions. Overall, we would highly recommend this software to other research teams!"
Maximize research potential
with innovative features.
Handle any medical
imaging format with ease.
Imalytics is designed to handle the full diversity of biomedical imaging data—no matter the format, system, or modality. Our platform supports seamless import, visualization, and analysis across PET, SPECT, CT, MRI, or optical imaging. We prioritize compatibility and interoperability so you can focus on insights, not data wrangling.
Imalytics supports a wide range of medical and research imaging file formats including DICOM, NIfTI, Analyze, TIFF stacks, and raw binary files—allowing researchers to plug in their data directly without needing custom conversion tools.
Whether your data comes from Bruker, MILabs, Mediso, Siemens, or other imaging systems, Imalytics is compatible across vendors. We’ve built our platform to integrate flexibly with your lab's existing equipment and data workflows.
Designed to handle the complexity of hybrid imaging, Imalytics supports simultaneous analysis of PET/CT, SPECT/MRI, optical/CT, and more. Our tools allow for seamless coregistration, visualization, and quantification across modalities.
Imalytics Preclinical uses the GFF format (.gff) by default to load and save underlay, overlay, segmentation, and project files. The file format supports multimodal, time-variant images while utilizing a lossless compression algorithm to reduce file size. Furthermore, a rich set of metadata is contained in the header and cryptographic hashing secures reading and writing. If you want to learn more about GFF, please refer to the publication by Grace et al. (full text here).
Frequently asked questions
Our image analysis software is not just cost-effective but also user-friendly, offering rapid, automated, and standardized image evaluation that enhances result quality and significantly improves throughput. Allow us to demonstrate its efficacy through a free demo.
Our software is designed to integrate into various workflows, providing centralized data analysis and encouraging collaboration thanks to its uniformity and compatibility with diverse imaging data. Additionally, it can be customized through our Python module, allowing for personal adjustments!
Absolutely. Our platform is intuitively designed, and our comprehensive tutorials minimize the learning curve. Your team can focus on their research, as the software accelerates and simplifies the analysis process.
Our software complements and enhances your existing methods, providing reproducible and standardized data analysis, validated by the community. By integrating your methods via our Python module, you can boost efficiency and broaden the applicability of your innovations.
While free options provide basic features, our paid solution delivers a comprehensive, sophisticated analysis platform. You gain access to advanced analytical tools, our professional support team, regular updates, and a community contributing to the software's continual development.
MILabs
Molecubes
Revvity (formerly PerkinElmer)
MRSolutions
Bruker
Siemens
Visual Sonics
SOFIE
Aspect
Philips
Mediso
Inviscan
GE Healthcare
CT imaging GmbH
TriFoil Imaging
Magnetic Insight
NeoScan
Comet Yxlon GmbH
SCANCO Medical
Xstrahl
United Imaging
Bioemtech
Sedecal
And many more!
The following file formats are supported:
Analyze (.hdr/.img)
Nifti (.nii/.hdr)
MicroPET (.hdr)
Vevo770 (.vsi)
Vevo2100 B-Mode, NonLinear, Linear (.bimg/.animg/.nbimg)
CT-Imaging Files (.mif/.mifx)
TIFF (.tif/.tiff)
MetaImageHeader (.mhd)
Sparse MHD (.sdr)
PAR/REC (.PAR)
NRRD (.nrrd)
NRRD Header Files (.nhdr)
PNG (.png)JPEG (.jpg)
SkyScan Recons (.log)
VFF files (.vff)
VOX files (.VOX)
Bitmap files (.bmp)
Aspect files (.dat)
CT Projections (.ori)
DICOM (.dcm)
Grace File Format (.gff)
Super marty View Files (.smv)
Interfile (.hdr)
And more!
1. Scope
1.1. Gremse-IT GmbH (“Licensor” or “Vendor”) provides software(“Software”), services and support to the customer (“Customer” or “Licensee”) subject to the terms and conditions („Terms and Conditions“) described in this document.
1.2. The Software comprises the compiled object code of the software and any documentation, including example data sets and tutorial videos provided with the software.
1.3. The Software may, depending on the contract, be licensed for use at a customer’s PC, which can by a virtual machine in a cloud hosted by a third party.
1.4. Gremse-IT provides services and support related to the use of the software.
1.5. The number of software licenses and the extent and duration of the support are regulated in a separate license and support agreement or quote.
2. Rights of Use
2.1. The licensee shall receive the non-transferable and non-exclusive right to install and use the software on specific computers of the customer (local PCs, servers or laptops, or cloud PCs). Gremse-IT provides an installer via download link. Installation of the software requires admin rights.
2.2. The use of the Gremse-IT software requires a PC with Microsoft Windows 64-bit operating system or an Apple computer with MacOS with at least 8GBmemory. Specific requirements may be mentioned in the quotation.
2.3. Gremse-IT recommends a computer with NVIDIA GPU with Cuda Compute Capability of at least 5.0. The customer needs to install a recent driver (not older than 6months) for the NVIDIA GPU. Without such a GPU, the software may be substantially slower, particularly on larger data sets.
2.4. Activation of the software requires a license file which is specific to the hardware system (PC) of the licensee. The hardware is encoded in a hash which is shown by our software at startup if a license is not found. The licensee is required to send the hash to Gremse-IT to receive a license file and place it at his computer to activate the software for this PC.
2.5. The license is valid and functional only for the PC the licensee provided the hash for. If the computer is broken, Gremse-IT will provide a new license for a new PC only within the duration of a support contract.
2.6. The licensee will not try to circumvent the licensing mechanism.
2.7. The installed software may restrict concurrent usage to a single or several concurrent users by means detecting the number of remote desktop connections. The number of allowed concurrent users may depend on the acquired license type. The licensee is not supposed to or allowed to circumvent this mechanism.
2.8. The Software and the program documentation supplied with the same are protected by copyright. Unless otherwise stated in the Software, the program description and/or the program documentation of, in relation to the customer, all rights in the Software shall be owned exclusively by Gremse-IT. With respect to components or modules from other producers (third-party software) supplied with the Software, in particular Open Source Software, the applicable license terms to which reference is made in the Software, the program description and/or the program documentation shall apply.
2.9. Any documents and training videos as to the use of Licensed Software provided by Gremse-IT may exclusively be copied and used for internal purposes only.
2.10. All other rights to the software shall be reserved for the licensor. Therefore, without the licensor’s prior written consent, the licensee shall not be entitled to reproduce or modify the software.
2.11. Any right of use granted in Licensed Software shall be limited to the Licensed Software in the object code and it shall not include the right to make any changes, to process and/or to modify Licensed Software in any other way. Inadmissible shall be retranslation of any program codes supplied to the Customer into other forms of code(decompilation) as well as any other types of reverse engineering of different production steps of Licensed Software; to the extent to which it cannot be waived, section 69e UrhG [Urheberrechtsgesetz – German Copyright Act] shall not be affected by this.
2.12. The Gremse-IT software is not intended and approved for diagnostic and therapeutic clinical use.
3. Term of the License
3.1. The license and support duration shall commence upon accepting the order.
3.2. The term of the license is shown on the confirmation of the order by Gremse-IT. In this respect, the following possibilities exist:
·Permanent license (includes a limited period of support)
·License for a definite time period (includes support for the time period).
4. Support
4.1. Gremse-IT shall provide support in case the software behaves erroneously or in disagreement with the provided documentation.
4.2. In case of an incident requiring support, the customer needs to inform Gremse-IT via email (support@gremse-it.com)and provide a description of the problem, to enable understanding or reproduction of the problem. The customer may also send example files to reproduce the problem which will be treated confidentially by Gremse-IT.
4.3. The duration of provided support is limited to the contracted period of support.
4.4. Gremse-IT will try to find a solution to the reported problem and reply swiftly to the customer (typically within 2 business days). The solution may involve sending a new version of the software to be installed by the customer which may take longer.
5. Liability
5.1. The software is provided and accepted by the licensee “as is”. Liability of the vendor will be limited to a maximum of the original purchase price of the software. Gremse-IT will not be liable for any general, special, incidental, or consequential damages including, but not limited to, loss of production, loss of profits, loss of revenue, loss of data, or any other business or any economical disadvantage suffered by the licensee arising out of the use or failure to use the software.
5.2. The vendor makes no warranty expressed or implied regarding the fitness of the software for a particular purpose or that the software will be suitable for the specific requirements of the Licensee.
5.3. The Vendor does not warrant that the use of the software will be uninterrupted or error-free. The Licensee accepts that software in general is prone to bugs and flaws within an acceptable level as determined in the industry.
5.4. Liability according to the German Product Liability Law (Produkthaftungsgesetz) for a possibly agreed upon guarantee and owing to a culpable damage to life, limb or health always remains unaffected.
5.5. Any liability of the Licensor for lost data shall be limited to compensatory damages in the amount necessary for restoration of the data using electronic backup media. The obligation of Licensee to back-up data on a regular basis according to the state of the art shall remain unaffected thereby.
5.6. Unless otherwise expressly regulated above, our liability is excluded.
6. Confidentiality
6.1. The customer shall keep the copy of the Software supplied via on-line download, delivered original data storage media, if any, as well as possible backup copies in a place that is secured against unauthorized access of third parties.
7. Final Provisions
7.1. There are no additional agreements to this Agreement. Alterations or additions shall be valid only if in writing. This written form requirement maybe waived only by a separate agreement, which itself must be in writing.
7.2. These terms shall also apply to later versions (Updates) and extensions (Upgrades) of the Software that is supplied to the customer during the term of the license, unless otherwise agreed at the time of the supply of the respective later version or extension.
7.3. This Agreement shall be subject to German law with the exception of the provisions of the United Nations Convention on Contracts for the International Sale of Goods (CISG) and such conflict-of-law rules according to which other than German law would be applicable. The place of jurisdiction shall be Gremse-IT’s place of business.
7.4. Should any provision of these Terms and Conditions be or become invalid, this shall not affect the validity of the remaining terms. The Parties shall in such an event be obliged to cooperate in the creation of terms which achieve such legally valid result as comes closest commercially to that of the invalid provision. The above shall apply accordingly to the closing of any gaps in these Terms and Conditions.
